On a recent overnight sail, I spent the night in Glover bight, a really nice anchorage. Very protected, deep water, with Tarpon Point marina, and the Westin Resort Cape Coral combining to make a very pleasurable place to overnight....or longer.
If your cruising in the SW Florida area, or transiting the Okeechobee Waterway, check it out.
ShaddO
"Bimini Basin" IN Cape Coral is good too - by a park, walk to grocery, nearby ice cream stand.